| Sabatier | Said | Saillen | Salamin |
| Salamolard | Salina | Sallamolard | Salzgeber |
| Salzmann | Sarbach | Sarrasin | Sartoretti |
| Saudan | Sauthier | Savioz | Schalbetter |
| Schallen (von) | Schaller | Schärtig | Schauben |
| Schenkel | Schers | Schiffmann | Schillig |
| Schiner | Schinner | Schlütter | Schmalzried |
| Schmelzbach | Schmidt | Schneller | Schnydrig |
| Schöpf | Schöpfer | Schreiber | Schröiter |
| Schuler | Schumacher | Schupbach | Schurmann |
| Schürmann | Schurwey | Schwarzen | Schwery |
| Schwestermann | Schwick | Schwitter | Schwizer |
| Sciclounof | Scotton | Senggen | Sépibus (de) |
| Seppey | Seppibus (de) | Sermier | Séverin |
| Sewer | Sevdoux | Siber | Sidler |
| Siegen | Siegwart | Sierre (de) | Sierro |
| Siess | Siggen | Sigmund | Sigrist |
| Sigristen | Silenen (von) | Silvestre | Silvestri |
| Silvetti | Simonetta | Simonini | Sirisin |
| Sneiders | Sodar | Sula | Solacio (de) |
| Solar | Solerio (de) | Solioz | Solleder |
| Solliard | Sostion | Sostionis | Soulas (de) |
| Sovy | Spagnoli | Spagnoly | Spahr |
| Specklv | Spiess | Spinelli | Spinner |
| Spohn | Sprung | Squaratti | Stalder |
| Stäli | Steffen | Steiger | Steiger (von) |
| Steineger | Steiner | Steinhaus | Steinhauser |
| Stepfer | Stephillen | Scweickhart | Sechal |
| Seeberger | Seematter | Sehr | Seiler |
| Selz | Sematter | Semblanet | Senfri |
| Sterren | Stockalper | Stocker | Stoeckli |
| Stoffel | Stüpfcr | Stoppini | Stragiotti |
| Streler | Stucky | Studer | Stupf |
| Stutz | Summermatter | Supersaxo | Supersaxo (de) |